Arabia was the “cornerstone” of the first human migrations out of Africa, study finds


Scientists have discovered that the Arabian Peninsula appears to have played an important role in the early human migrations from Africa. (Image credit: Shutterstock)

The largest study ever of the Arab genome reveals the oldest of the modern Middle Eastern population and that modern humans may have first spread around the world.

Today, the Arabian Peninsula, which includes Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab Emirates, has long served as an important crossroads between Africa, Europe and Asia. Archeology, With fossils DNA The results suggest that analysis of the Middle East and its people may reveal more about how modern people initially behaved. Escaped from Africa And for the rest of the world.

So far, little research has been done on Arab genetics. In a new study, researchers have performed the first large-scale analysis of the genetics of the Middle East’s population, examining the DNA of 6,218 adults randomly selected from the Qatar Health Database, now available elsewhere in the world. In relation to the DNA of the inhabitants of the region. DNA from ancient humans who once lived in Africa, Europe and Asia.

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“This is the first major study on the Arab population,” Younes Mokrab, co-author of the research co-author, head of the medical and collective genomics laboratory at Sidra Medicine in Doha, told Live Science. Qatar.

Scientists have found that DNA from groups in the Middle East has made important genetic contributions to communities in Europe, South Asia, and even South America. These groups, they said.

“Arab ancestors are an important ancestral component of many modern populations,” Moclub said. “This means that what is discovered in this area has a direct impact on the population of other areas.”

New findings also suggest that the ancestors of the Arabian Peninsula group separated from the first Africans around 90,000 years ago. This was around the same time that European and South Asian ancestors separated from the first Africans, supporting the idea that people migrated from Africa to other parts of the world via Arabia. The researchers said.

“Arabia is the base for early migration from Africa,” Moclub said.

Later, the Arabian Peninsula group clearly separated from its European ancestors around 42,000 years ago and from the South Asian population around 32,000 years ago. “Previously, the Arab population was thought to come from a wide range of European populations,” Moclub said.

(Image credit: Shutterstock)

After modern humans left Africa, they encountered other now extinct – and sometimes mated – human pedigrees. Neanderthals And the Denisovans whose ancestors left Africa long before the departure of modern humans and were almost exclusively discovered in Europe and Asia. “The timeline found in our study when the Arabs diverged from other populations is the reason why Neanderthal DNA is much rarer in the Arab population than in the later mixed population with the ancient Hominini. Explains,” Moclub a declared.

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Additionally, after comparing the modern human genome with ancient human DNA, scientists have found that a unique group of Arabs from the peninsula may be the oldest of all modern populations in the Middle East, Moclub said. . Members of this group may be the closest relatives of the first known peasants and hunter-gatherers to occupy the ancient Middle East, the researchers said.

Scientists said the ancestral Arab group appeared to have experienced multiple divisions 12,000 to 20,000 years ago. This corresponds to Arabia’s arid path, with some groups moving to more fertile areas to create a community of settlers and others living in arid areas that further favor the nomadic way of life. I continue.

A new study has found a high rate of inbreeding in several groups in the Arabian Peninsula dating back to ancient times. This is probably because the tribal nature of these cultures raises barriers to marriage outside of the tribal group. These new findings reveal the causes of specific hereditary diseases and the communities shown in the study, as incest can highlight rare mutations that can increase the risk of the disease. The researchers said it could lead to precision medicine that would help diagnose and treat the disease.

Scientists detailed the results online in the journal on October 12. Nature Communication..

Originally published in Live Science.

Arabia was the “cornerstone” of the first human migrations out of Africa, study finds Arabia was the “cornerstone” of the first human migrations out of Africa, study finds

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